منابع مشابه
Prognostic Value of Lymph Node Ratio in comparison to Lymph Node Metastases in Stage III Colon Cancer
Background & Objectives: Colon cancer is currently of high incidence and mortality rate. Identifying the factors influencing its prognosis can be very beneficial to its clinical treatment. Recent studies have shown that lymph nodes ratio can be considered as an important prognostic factor. The aim of the present study is to investigate the effect of this factor on the prognosis of the ...
متن کاملPolymorphisms in VEGF and IL-8 predict tumor recurrence in stage III colon cancer.
BACKGROUND Identifying molecular markers for tumor recurrence is critical in successfully selecting patients with stage III colon cancer who are more likely to benefit from adjuvant chemotherapy. The present study analyzed a subset of 10 polymorphisms within eight genes involved in the tumor angiogenesis pathway and their impact on prognosis in stage III colon cancer patients treated with adjuv...
متن کاملLymph node ratio predicts tumor recurrence in stage III colon cancer.
OBJECTIVE To evaluate the lymph node ratio as a predictor for tumor recurrence in stage III colon cancer patients. METHODS Patients with stage III colon cancer who underwent curative resection between January 2005 and December 2010 were retrospectively reviewed. The main outcomes were tumor recurrence and death. The impact of lymph node ratio and other clinicopathological factors on disease-f...
متن کاملAdjuvant Systemic Therapy in Stage II and III Colon Cancer
The prognosis of colon cancer is primarily determined through staging of the disease. After curative surgery, clinically occult micrometastases are thought to be the major source of disease recurrence. The main aim of postoperative systemic treatment is to eradicate micrometastases, thereby improving outcomes with an increased cure rate. Adjuvant systemic chemotherapy is indicated for patients ...
متن کاملCDX2 as a Prognostic Biomarker in Stage II and Stage III Colon Cancer.
Background The identification of high-risk stage II colon cancers is key to the selection of patients who require adjuvant treatment after surgery. Microarray-based multigene-expression signatures derived from stem cells and progenitor cells hold promise, but they are difficult to use in clinical practice. Methods We used a new bioinformatics approach to search for biomarkers of colon epithelia...
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ژورنال
عنوان ژورنال: American Journal of Clinical Oncology
سال: 2019
ISSN: 0277-3732
DOI: 10.1097/coc.0000000000000645